Mut zur Veränderung
نویسندگان
چکیده
منابع مشابه
Empirische Untersuchung zur Veränderung des Studienalltags durch Einführung eines Lernmanagementsystems
In einer Fragebogenstudie wurde der unterstützende Effekt eines Lernmanagementsystems (LMS) auf verschiedene Handlungsbereiche von Studierenden bewertet. Hierbei wurden speziell differenzielle Aspekte wie Anzahl der Studiensemester, Zugehörigkeit zu Fachbereichen/Fakultäten und das Geschlecht der Befragten berücksichtigt. Die Ergebnisse der Studie zeigen einen insgesamt positiven Einfluss des L...
متن کاملMethylmalonic Acidemia with Novel MUT Gene Mutations
A 5-year-old boy presented with recurrent episodes of fever, feeding problems, lethargy, from the age of 11 months, and poor weight gain. He was admitted and evaluated for metabolic causes and diagnosed as having methylmalonic acidemia (MMA). He was treated with vit B12 and carnitine supplements and has been on follow-up for the last 3 years. Mutation analysis by next generation sequencing (NGS...
متن کاملHuman Mut T homolog 1 (MTH1)
Oncogenic RAS-induced reactive oxygen species (ROS) trigger barriers to cell transformation and cancer progression through tumor-suppressive responses such as cellular senescence or cell death. We have recently shown that oncogenic RAS-induced DNA damage and attendant premature senescence can be prevented by overexpressing human MutT Homolog 1 (MTH1), the major mammalian detoxifier of the oxidi...
متن کاملGenetic characterization of a MUT locus mutation discriminating heterogeneity in mut0 and mut- methylmalonic aciduria by interallelic complementation.
Genetic complementation of fibroblasts from patients with methylmalonic aciduria (MMA) defines a unique class of allelic mutations arising from mutations at the locus encoding the methylmalonyl coenzyme A (CoA) mutase apoenzyme. Various phenotypes of MMA have been delineated including complete absence of enzyme activity (mut0) and abnormal enzyme activity with an elevated Km for adenosylcobalam...
متن کاملThe basolateral expression of mUT-A3 in the mouse kidney.
Facilitative UT-A urea transporters play a central role in the urinary concentrating mechanism. There are three major UT-A isoforms found in the mouse kidney: mUT-A1, mUT-A2, and mUT-A3. The major aim of this study was to identify the location and function of mUT-A3. UT-A proteins were investigated using three novel mouse UT-A-targeted antibodies: ML446, MQ2, and ML194. ML446 detected mUT-A1 an...
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ژورنال
عنوان ژورنال: Wiener klinisches Magazin
سال: 2014
ISSN: 1869-1757,1613-7817
DOI: 10.1007/s00740-014-0015-4